Article
Multi-institutional prostate cancer study of genetic susceptibility in populations of African descent.
Carcinogenesis - 1 Sept 2011
Taioli Emanuela, Flores-Obando Rafael E, Agalliu Ilir, Blanchet Pascal, Bunker Clareann H, Ferrell Robert E, Jackson Maria, Kidd La Creis R, Kolb Suzanne, Lavender Nicol A, McFarlane-Anderson Norma, Morrison Seian S, Multigner Luc, Ostrande Elaine A, Park Jong Y, Patrick Alan L, Rebbeck Timothy R, Romana Marc, Stanford Janet L, Ukoli Flora, Vancleave Tiva T, Zeigler-Johnson Charnita M, Mutetwa Batsirai, Ragin Camille
Abstract excerpt
Prostate cancer disparities have been reported in men of African descent who show the highest incidence, mortality, compared with other ethnic groups. Few studies have explored the genetic and environmental factors for prostate cancer in men of African ancestry. The glutathione-S-transferases family conjugates carcinogens before their excretion and is expressed in prostate tissue. This study addressed the role of...
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