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Article

Copy number variation of GSTT1 and GSTM1 and the risk of prostate cancer in a Caribbean population of African descent.

PloS one - 1 Jan 2014

Emeville Elise, Broquère Cédric, Brureau Laurent, Ferdinand Séverine, Blanchet Pascal, Multigner Luc, Romana Marc

Abstract excerpt

BACKGROUND: Deletions of the glutathione S-transferase genes M1 and T1 (GSTM1 and GSTT1) have been studied as potential risk factors for prostate cancer. Conflicting results have been obtained. Moreover, most such studies could not discriminate heterozygous from homozygous carriers of the non-deleted alleles. OBJECTIVE: We investigated whether copy number variation (CNV) of the GSTM1 and/or GSTT1 genes contribute...

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Source

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Identifiers

PMID: 25198353
DOI: 10.1371/journal.pone.0107275
PMCID: PMC4157893

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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