Article
A polymorphism of the interferon-gamma-inducible protein 30 gene is associated with hyperglycemia in severely obese individuals.
Human genetics - 1 Jan 2012
Turcot V, Bouchard L, Faucher G, Tchernof A, Deshaies Y, Pérusse L, Marceau P, Hould F S, Lebel S, Vohl Marie-Claude
Abstract excerpt
A previous expression profiling of visceral adipose tissue (VAT) revealed that the immune response gene interferon-gamma-inducible protein 30 (IFI30) gene was 1.72-fold more highly expressed in non-diabetic severely obese men with the metabolic syndrome as compared to those without. Given the importance of low-grade inflammation in obesity-related metabolic complications, we hypothesized that variants in the...
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