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Relation of serum IL-32 levels and gene polymorphism rs45499297 with obesity in Mexican patients: a laboratory and in silico analysis.

Nutricion hospitalaria - 29 Mar 2022

Martínez Pérez Luz Andrea, Becerra-Ruiz Julieta Sarai, García-Aviña Juana Esther, González-Sánchez Grecia Denisse, Martínez-Esquivias Fernando, Vázquez-Jiménez Sonia Isela, Ramírez-De Los Santos Saúl, López-Pulido Edgar Iván, Guzmán-Flores Juan Manuel

Abstract excerpt

Introduction: Background: many genes have been involved in the development of obesity. Interleukin 32 (IL-32) is a proinflammatory cytokine; rs45499297 is a T/C promoter, single-nucleotide polymorphism of the IL32 gene. Objectives: this study aimed to evaluate the rs45499297 polymorphism and its association with obesity. Another objective of this study was to carry out an in silico analysis. Methods: this study...

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PMID: 35156380
DOI: 10.20960/nh.03804

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