Article
DPP4 gene DNA methylation in the omentum is associated with its gene expression and plasma lipid profile in severe obesity.
Obesity (Silver Spring, Md.) - 1 Feb 2011
Turcot Valérie, Bouchard Luigi, Faucher Geneviève, Tchernof André, Deshaies Yves, Pérusse Louis, Bélisle Alexandre, Marceau Simon, Biron Simon, Lescelleur Odette, Biertho Laurent, Vohl Marie-Claude
Abstract excerpt
Severely obese subjects with the metabolic syndrome (MS) have higher dipeptidyl peptidase-4 (DPP4) expression in their visceral adipose tissue (VAT) compared to obese individuals without MS. We tested the hypothesis that methylation level of CpG sites in the DPP4 promoter CpG island in VAT was ge...
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