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Article

The GDF15 3' UTR Polymorphism rs1054564 Is Associated with Diabetes and Subclinical Atherosclerosis.

International journal of molecular sciences - 7 Nov 2024

Guardiola Montse, Girona Josefa, Barroso Emma, García-Altares María, Ibarretxe Daiana, Plana Núria, Ribalta Josep, Correig Xavier, Vázquez-Carrera Manuel, Masana Lluís, Rodríguez-Calvo Ricardo

Abstract excerpt

Growth differentiation factor 15 (GDF15) is a stress-response cytokine related to a wide variety of metabolic diseases. However, the impact of GDF15-specific genetic variants on the abovementioned conditions is poorly known. The aim of this study was to assess the impact of selected GDF15 single-nucleotide polymorphisms (SNPs) on metabolic disturbances and subclinical atherosclerosis. A cross-sectional study...

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Identifiers

PMID: 39596055
DOI: 10.3390/ijms252211985
PMCID: PMC11593611

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