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Article

Increased Ifi202b/IFI16 expression stimulates adipogenesis in mice and humans.

Diabetologia - 1 May 2018

Stadion Mandy, Schwerbel Kristin, Graja Antonia, Baumeier Christian, Rödiger Maria, Jonas Wenke, Wolfrum Christian, Staiger Harald, Fritsche Andreas, Häring Hans-Ulrich, Klöting Nora, Blüher Matthias, Fischer-Posovszky Pamela, Schulz Tim J, Joost Hans-Georg, Vogel Heike, Schürmann Annette

Abstract excerpt

AIMS/HYPOTHESIS: Obesity results from a constant and complex interplay between environmental stimuli and predisposing genes. Recently, we identified the IFN-activated gene Ifi202b as the most likely gene responsible for the obesity quantitative trait locus Nob3 (New Zealand Obese [NZO] obesity 3). The aim of this study was to evaluate the effects of Ifi202b on body weight and adipose tissue biology, and to...

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Share to 3T3-L1 Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Adipose Tissue, White

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Source

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Identifiers

PMID: 29478099
DOI: 10.1007/s00125-018-4571-9
PMCID: PMC6448999

Genes

IFI16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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