Article
Genetic contribution to C-reactive protein levels in severe obesity.
Molecular genetics and metabolism - 1 Mar 2012
Faucher Geneviève, Guénard Frédéric, Bouchard Luigi, Garneau Véronique, Turcot Valérie, Houde Alain, Tchernof André, Bergeron Jean, Deshaies Yves, Hould Frédéric-Simon, Lebel Stéfane, Marceau Picard, Vohl Marie-Claude
Abstract excerpt
Obese individuals are characterized by a chronic, low-grade inflammatory state. Increased levels of C-reactive protein (CRP), a marker of inflammation, have been observed in subjects with the metabolic syndrome. We have previously reported that genes encoding proteins involved in the anti-inflammatory and immune response are differentially expressed in visceral adipose tissue of obese men with or without the...
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