Article
Single nucleotide polymorphisms of RAD51 G135C, XRCC2 Arg188His and XRCC3 Thr241Met homologous recombination repair genes and the risk of sporadic endometrial cancer in Polish women.
The journal of obstetrics and gynaecology research - 1 Jun 2012
Romanowicz-Makowska Hanna, Smolarz Beata, Połać Ireneusz, Sporny Stanisław
Abstract excerpt
BACKGROUND: The genes RAD51, XRCC2 and XRCC3 encode proteins that are important for the repair of double-strand DNA breaks by homologous recombination. Therefore, genetic variability in these genes may contribute to the occurrence and progression of endometrial cancer. METHODS: The subject of investigation in the reported study was the distribution of genotypes and the prevalence of alleles of the RAD51 G135C,...
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