Article
Structural and functional characterization of the gamma 1 subunit of GABAA/benzodiazepine receptors.
The EMBO journal - 1 Oct 1990
Ymer S, Draguhn A, Wisden W, Werner P, Keinänen K, Schofield P R, Sprengel R, Pritchett D B, Seeburg P H
Abstract excerpt
The GABAA receptor gamma 1 subunit of human, rat and bovine origin was molecularly cloned and compared with the gamma 2 subunit in structure and function. Both gamma subunit variants share 74% sequence similarity and are prominently synthesized in often distinct areas of the central nervous syste...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Brain
- Cattle
- Cloning, Molecular
- DNA
- Gene Library
- Genetic Variation
- Humans
- Macromolecular Substances
- Molecular Sequence Data
- Nucleic Acid Hybridization
- Oligonucleotide Probes
- RNA, Messenger