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Article

Structural and functional characterization of the gamma 1 subunit of GABAA/benzodiazepine receptors.

The EMBO journal - 1 Oct 1990

Ymer S, Draguhn A, Wisden W, Werner P, Keinänen K, Schofield P R, Sprengel R, Pritchett D B, Seeburg P H

Abstract excerpt

The GABAA receptor gamma 1 subunit of human, rat and bovine origin was molecularly cloned and compared with the gamma 2 subunit in structure and function. Both gamma subunit variants share 74% sequence similarity and are prominently synthesized in often distinct areas of the central nervous system as documented by in situ hybridization. When co-expressed with alpha and beta subunits in Xenopus oocytes and...

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Identifiers

PMID: 2170110
DOI: 10.1002/j.1460-2075.1990.tb07525.x
PMCID: PMC552059

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