Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ADP-ribosylarginine hydrolase regulates cell proliferation and tumorigenesis.

Cancer research - 1 Aug 2011

Kato Jiro, Zhu Jianfeng, Liu Chengyu, Stylianou Mario, Hoffmann Victoria, Lizak Martin J, Glasgow Connie G, Moss Joel

Abstract excerpt

Protein ADP-ribosylation is a reversible posttranslational modification of uncertain significance in cancer. In this study, we evaluated the consequences for cancer susceptibility in the mouse of a genetic deletion of the enzyme responsible for removing mono-ADP-ribose moieties from arginines in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Diphosphate Ribose
Share to Loss of Heterozygosity
Share to Mice, Nude

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to N-Glycosyl Hydrolases

Share to Neoplasm Metastasis

Share to Neoplasms, Experimental

Share to Protein Processing, Post-Translational

Share to Tumor Stem Cell Assay

Source

Open in PubMed Open full text

Identifiers

PMID: 21697277
DOI: 10.1158/0008-5472.CAN-10-0733
PMCID: PMC3399181

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21697277-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ADP-ribosylarginine hydrolase regulates cell proliferation and tumorigenesis.PMID 21697277Read ↗

<i>ADP-ribose-acceptor hydrolase 2</i> ( <i>Arh2</i> ) deficiency results in cardiac dysfunction, tumorigenesis, inflammation, and decreased survivalSemantic proximity Read ↗

Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human diseaseSemantic proximity Read ↗

Identification and characterization of a mammalian 39-kDa poly(ADP-ribose) glycohydrolase.Semantic proximity Read ↗

ADP-ribosylation signalling and human diseaseSemantic proximity Read ↗

Arginine reprogramming in ADPKD results in arginine-dependent cystogenesis.Semantic proximity Read ↗

A mouse PRMT1 null allele defines an essential role for arginine methylation in genome maintenance and cell proliferation.Semantic proximity Read ↗

Genomic organization and promoter analysis of the mouse ADP-ribosylarginine hydrolase gene.Semantic proximity Read ↗

Poly(ADP-ribosyl)ation in relation to cancer and autoimmune disease.Semantic proximity Read ↗

Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine.Semantic proximity Read ↗

Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair.Semantic proximity Read ↗

Poly (ADP-ribose) glycohydrolase regulates retinoic acid receptor-mediated gene expression.Semantic proximity Read ↗

Oncogenic activity of poly (ADP-ribose) glycohydrolaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.