Article
Expression of a human T-cell protein-tyrosine-phosphatase in baby hamster kidney cells.
Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 1990
Cool D E, Tonks N K, Charbonneau H, Fischer E H, Krebs E G
Abstract excerpt
A human T-cell cDNA encoding a 48-kDa protein-tyrosine-phosphatase (PTPase; protein-tyrosine-phosphate phosphohydrolase, EC 3.1.3.48) was cloned into a mammalian expression vector and introduced into baby hamster kidney cells, and stable colonies were isolated. The expressed PTPase was found to b...
Topics
- Animals
- Base Sequence
- Cell Line
- Chromatography, High Pressure Liquid
- Cricetinae
- Gene Expression
- Humans
- Immune Sera
- Kidney
- Molecular Sequence Data
- Molecular Weight
- Mutation
- Oligonucleotide Probes
- Phosphoprotein Phosphatases
- Plasmids
- Protein Conformation
- Protein Tyrosine Phosphatases
- T-Lymphocytes