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Article

Properties of a baculovirus mutant defective in the protein phosphatase gene.

Journal of virology - 1 Jul 1995

Li Y, Miller L K

Abstract excerpt

Autographa california nuclear polyhedrosis virus (AcMNPV) contains a gene, ptp, encoding a protein tyrosine/serine phosphatase, BV-PTP. To investigate the biological function of ptp in the baculoviral replication cycle, we constructed a recombinant baculovirus, vPTPdel, in which the catalytically active site of BV-PTP was deleted. Although the vPTPdel mutant was viable in cell culture, it was partially defective...

Topics

Amino Acid Sequence
Animals
Cell Line
Gene Deletion
Genes, Viral
Molecular Sequence Data
Mutation
Nucleopolyhedroviruses
Phosphorylation
Protein Tyrosine Phosphatases
Proteins
Spodoptera

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Virulence

Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 7769718
DOI: 10.1128/JVI.69.7.4533-4537.1995
PMCID: PMC189200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7769718-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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