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Article

Properties of a baculovirus mutant defective in the protein phosphatase gene.

Journal of virology - 1 Jul 1995

Li Y, Miller L K

Abstract excerpt

Autographa california nuclear polyhedrosis virus (AcMNPV) contains a gene, ptp, encoding a protein tyrosine/serine phosphatase, BV-PTP. To investigate the biological function of ptp in the baculoviral replication cycle, we constructed a recombinant baculovirus, vPTPdel, in which the catalytically active site of BV-PTP was deleted. Although the vPTPdel mutant was viable in cell culture, it was partially defective...

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Identifiers

PMID: 7769718
DOI: 10.1128/JVI.69.7.4533-4537.1995
PMCID: PMC189200

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