Article
Biochemical, genetic and ultrastructural defects in a mitochondrial mutant (ER-3) of Neurospora crassa with senescence phenotype.
Mechanisms of ageing and development - 1 Jul 1990
Niagro F D, Mishra N C
Abstract excerpt
The structural and functional abnormalities in a new respiratory deficient, mitochondrial senescence mutant ER-3 of Neurospora crassa are described. The mitochondrial mutant, which grows at a rate of only 10% of that of the wild type, was found deficient in all three cytochromes, and completely lacking in cytochromes aa3. Cytochrome oxidase activity in the mutant mitochondria was only about 5% of the wild type...
Topics
- Aging
- Culture Media
- Cytochromes
- DNA, Fungal
- Electron Transport Complex IV
- Genes, Fungal
- Microscopy, Electron
- Mitochondria
- Mutation
- Neurospora
- Neurospora crassa