Article
The external alternative NAD(P)H dehydrogenase NDE3 is localized both in the mitochondria and in the cytoplasm of Neurospora crassa.
Journal of molecular biology - 11 May 2007
Carneiro Patrícia, Duarte Margarida, Videira Arnaldo
Abstract excerpt
The filamentous fungus Neurospora crassa has a branched respiratory chain. Several alternative dehydrogenases, aside from the canonical complex I enzyme, are involved in the oxidation of NAD(P)H substrates. Based on homology searches in the fungal genome, we have tentatively identified one of these proteins. The corresponding gene was inactivated by the generation of repeat-induced point mutations and a...
Topics
- Amino Acid Sequence
- Cell Respiration
- Cytoplasm
- Fungal Proteins
- Green Fluorescent Proteins
- Mitochondria
- Molecular Sequence Data
- Mutation
- NADP
- NADPH Dehydrogenase
- Neurospora crassa
- Recombinant Fusion Proteins
- Up-Regulation
