Article
Genetic evidence for a regulatory pathway controlling alternative oxidase production in Neurospora crassa.
Genetics - 1 Jan 2005
Descheneau Andrea T, Cleary Ian A, Nargang Frank E
Abstract excerpt
When the cytochrome-mediated mitochondrial electron transport chain of Neurospora crassa is disrupted, an alternative oxidase encoded by the nuclear aod-1 gene is induced. The alternative oxidase donates electrons directly to oxygen from the ubiquininol pool and is insensitive to chemicals such as antimycin A and KCN that affect the standard electron transport chain. To facilitate isolation of mutants affecting...
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