Article
Influence of HLA-DQ2 and DQ8 on severity in celiac Disease.
Journal of clinical gastroenterology - 1 Jan 2012
Biagi Federico, Bianchi Paola I, Vattiato Claudia, Marchese Alessandra, Trotta Lucia, Badulli Carla, De Silvestri Annalisa, Martinetti Miryam, Corazza Gino R
Abstract excerpt
BACKGROUND: HLA-DQB1*02 homozygosity was shown to be more common in patients with complicated rather than uncomplicated celiac disease (CD). GOALS: To study HLA-DQA1 and DQB1 profile in adult patients with different forms of CD, including patients with complicated and potential CD, the most affected and the most preserved histologic end of the pathologic celiac spectrum. STUDY: HLA-DQA1 and DQB1 molecular typing...
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