Article
Genome-wide Association study using pooled DNA to identify candidate markers mediating susceptibility to postoperative nausea and vomiting.
Anesthesiology - 1 Jul 2011
Janicki Piotr K, Vealey Ryan, Liu Jiabin, Escajeda Jeremiah, Postula Marek, Welker Kelli
Abstract excerpt
BACKGROUND: A family history has been established as a risk factor for postoperative nausea and vomiting (PONV), but the identities of susceptibility genes remain unknown. The goal of this study was to identify the genetic loci that may contribute to PONV susceptibility in an adult population. METHODS: The authors performed a genome-wide association study involving pooling of DNA obtained from 122 patients with...
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