Epstein-Barr virus-associated T/natural killer-cell lymphoproliferative disorder in children and young adults has similar molecular signature to extranodal nasal natural killer/T-cell lymphoma but shows distinctive stem cell-like phenotype.

doi:10.3109/10428194.2014.983099

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Epstein-Barr virus-associated T/natural killer-cell lymphoproliferative disorder in children and young adults has similar molecular signature to extranodal nasal natural killer/T-cell lymphoma but shows distinctive stem cell-like phenotype.

Leukemia & lymphoma - 1 Jan 2015

Ng Siok-Bian, Ohshima Koichi, Selvarajan Viknesvaran, Huang Gaofeng, Choo Shoa-Nian, Miyoshi Hiroaki, Shimizu Norio, Reghunathan Renji, Chua Hsin-Chieh, Yeoh Allen Eng-Juh, Quah Thuan-Chong, Koh Liang-Piu, Tan Poh-Lin, Chng Wee-Joo

Abstract excerpt

We performed gene expression profiling in Epstein-Barr virus (EBV)-associated T/natural killer (NK)-cell lymphoproliferative disorder in children and young adults (TNKLPDC) in order to understand the molecular pathways deregulated in this disease and compared it with nasal-type NK/T-cell lymphoma (NKTL). The molecular and phenotypic signature of TNKLPDC is similar to NKTL, with overexpression of p53, survivin and...

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PMID: 25382618
DOI: 10.3109/10428194.2014.983099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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