Article

Integrated transcriptomic and proteomic analyses identify novel biomarkers of bladder outlet obstruction

2026-05-04

Abstract excerpt

Bladder outlet obstruction leads to pathological remodeling and emergence of lower urinary tract symptoms. Although relief of obstruction is associated with symptomatic improvement, it is not universally successful, reflecting persistent alterations in the bladder. Reliable surrogate biomarkers of obstruction are lacking, particularly early in the disease course before irreversible damage to the bladder may have o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 157c0ed5-0be4-5530-8d59-7f53cf835d90
DOI: 10.64898/2026.04.29.721732

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Integrated transcriptomic and proteomic analyses identify novel biomarkers of bladder outlet obstructionDOI 10.64898/2026.04.29.721732Read

Characterization of miRNA-regulated networks, hubs of signaling, and biomarkers in obstruction-induced bladder dysfunctionSemantic proximity Read

Systems analysis of benign bladder disorders: insights from omics analysis.Semantic proximity Read

Human - murine concordance of molecular signatures in nerve-sparing murine partial bladder outlet obstruction (NeMO)Semantic proximity Read

Single-Cell Transcriptomic Map of the Human and Mouse BladdersSemantic proximity Read

A new role for IFRD1 in regulation of ER stress in bladder epithelial homeostasisSemantic proximity Read

Partial Bladder Outlet Obstruction in Mice May Cause E-Cadherin Repression through Hypoxia Induced PathwaySemantic proximity Read

CircRNA/miRNA/mRNA axis participates in the progression of bladder outlet obstructionSemantic proximity Read

Machine Learning-based Classification of transcriptome Signatures of non-ulcerative Bladder Pain SyndromeSemantic proximity Read

Single‐cell transcriptomes of mouse bladder urothelium uncover novel cell type markers and urothelial differentiation characteristicsSemantic proximity Read

Urinary miRNA profiles discriminate between obstruction-induced bladder dysfunction and healthy controlsSemantic proximity Read

A Cellular Reference Resource for the Mouse Urinary BladderSemantic proximity Read

A Review of the Etiopathology of Phenotypes in Interstitial Cystitis/Bladder Pain Syndrome.Semantic proximity Read