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Article

Single-nucleotide polymorphisms (SNPs) of the IRF6 and TFAP2A in non-syndromic cleft lip with or without cleft palate (NSCLP) in a northern Chinese population.

Biochemical and biophysical research communications - 15 Jul 2011

Shi Jinna, Song Tao, Jiao Xiaohui, Qin Chunlin, Zhou Jin

Abstract excerpt

Non-syndromic cleft lip with or without cleft palate (NSCLP) is a common birth defect that is presumably caused by genetic factors alone or gene alterations in combination with environmental changes. A number of studies have shown an association between NSCLP and single-nucleotide polymorphisms (SNPs) in the interferon regulatory factor 6 (IRF6) gene in several populations. The transcription factor AP-2a...

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PMID: 21683068
DOI: 10.1016/j.bbrc.2011.06.006

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