Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[ABC transporters' impact on effect and metabolism of drugs].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke - 3 Jun 2011

Slåtsve Arne Martin, Ravna Aina Westrheim, Lyså Roy Andre, Sager Georg

Abstract excerpt

BACKGROUND: Drugs must be transported to reach the site of action and to be removed from the body. Several proteins within the large family of ABC transporters (ATP-binding domain), are important for pharmacokinetics. In this review article we present, from a clinical point of view, ABC transporters that are known to be important for basic and clinical pharmacology. MATERIAL AND METHOD: This overview is based on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP-Binding Cassette Transporters
Share to Biological Availability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood-Brain Barrier

Share to Gastrointestinal Tract

Share to Multidrug Resistance-Associated Proteins

Share to Pharmacogenetics

Share to Pharmacokinetics

Share to Precision Medicine

Source

Identifiers

PMID: 21681236
DOI: 10.4045/tidsskr.10.0675

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[ABC transporters' impact on effect and metabolism of drugs].PMID 21681236Read ↗

Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature.Semantic proximity Read ↗

Functional Significance of Genetic Polymorphisms in P-glycoprotein (MDR1, ABCB1) and Breast Cancer Resistance Protein (BCRP, ABCG2)Semantic proximity Read ↗

[MDR1 (ABCB1) gene encoding glycoprotein P (P-gp), a member of ABC transporter superfamily: consequences for therapy and progression of neoplastic diseases].Semantic proximity Read ↗

Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.Semantic proximity Read ↗

ATP Binding Cassette Transporters and Cancer: Revisiting Their Controversial RoleSemantic proximity Read ↗

Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters.Semantic proximity Read ↗

Influence of multidrug resistance and drug transport proteins on chemotherapy drug metabolismSemantic proximity Read ↗

ATP‐binding cassette (ABC) transporters in cancer: A review of recent updatesSemantic proximity Read ↗

ABC transporters: human disease and pharmacotherapeutic potentialSemantic proximity Read ↗

Transporters and drug-drug interactions: important determinants of drug disposition and effects.Semantic proximity Read ↗

Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.Semantic proximity Read ↗

Transporters and Their Impact on Drug DispositionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.