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Article

Epidermal growth factor receptor mutations are associated with docetaxel sensitivity in lung cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Oct 2011

Yoshimasu Tatsuya, Oura Shoji, Ohta Fuminori, Hirai Yoshimitsu, Naito Koma, Nakamura Rie, Nishiguchi Haruka, Hashimoto Sayoko, Kawago Mitsumasa, Okamura Yoshitaka

Abstract excerpt

INTRODUCTION: A recent large randomized controlled trial revealed that patients with lung cancer with epidermal growth factor receptor (EGFR) mutations had better prognoses when treated with the EGFR-tyrosine kinase inhibitor, gefitinib, than with cytotoxic chemotherapeutic agents. Lung cancer with EGFR mutations is highly sensitive to EGFR-tyrosine kinase inhibitors. The previous trial implied that EGFR...

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Source

Identifiers

PMID: 21681119
DOI: 10.1097/JTO.0b013e318221f71a

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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