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Article

Histoculture drug response assay for gefitinib in non-small-cell lung cancer.

General thoracic and cardiovascular surgery - 1 Mar 2009

Yoshimasu Tatsuya, Ohta Fuminori, Oura Shoji, Tamaki Takeshi, Shimizu Yukio, Naito Koma, Kiyoi Megumi, Hirai Yoshimitsu, Kawago Mitsumasa, Okamura Yoshitaka

Abstract excerpt

OBJECTIVE: There are many predictive factors for gefitinib sensitivity, including epidermal growth factor receptor (EGFR) gene mutation, EGFR copy number, and k-ras mutation. To investigate all of them is too expensive. We evaluated the chemosensitivity for gefitinib in non-small-cell lung cancer (NSCLC) using a histoculture drug response assay (HDRA). METHODS: Surgically resected fresh tumor specimens from 22...

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Identifiers

PMID: 19280309
DOI: 10.1007/s11748-008-0332-x

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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