Article
p53 is associated with p34cdc2 in transformed cells.
The EMBO journal - 1 Sept 1990
Milner J, Cook A, Mason J
Abstract excerpt
The normal functioning of p53 is thought to involve p53 target proteins. We have previously identified a cellular 35 kd protein associated with p53 and now report evidence identifying this 35 kd protein as p34cdc2, product of the cell cycle control cdc2 gene. The association between p53 and p34cd...
Topics
- Animals
- Antigens, Polyomavirus Transforming
- CDC2 Protein Kinase
- Cell Line
- Cell Transformation, Neoplastic
- Mice
- Mutation
- Nuclear Proteins
- Oncogene Proteins
- Peptide Mapping
- Phosphoproteins
- Protein Kinases
- Simian virus 40
- Tumor Suppressor Protein p53
