Article
Conserved sequences in enzymes of the UDP-GlcNAc/MurNAc family are essential in hamster UDP-GlcNAc:dolichol-P GlcNAc-1-P transferase.
Glycobiology - 1 Jun 1998
Dal Nogare A R, Dan N, Lehrman M A
Abstract excerpt
The UDP-GlcNAc/MurNAc family of eukaryotic and prokaryotic enzymes use UDP-GlcNAc or UDP-MurNAc-pentapeptide as donors, dolichol-P or polyprenol-P as acceptors, and generate sugar-P-P-polyisoprenols. A series of six conserved sequences, designated A through F and ranging from 5 to 13 amino acid r...
Topics
- Amino Acid Sequence
- Animals
- Bacterial Proteins
- CHO Cells
- Conserved Sequence
- Cricetinae
- Escherichia coli
- Gene Expression
- Gene Targeting
- Mutagenesis, Site-Directed
- Mutation
- Peptide Synthases
- Protein Folding
- Recombinant Proteins
- Recombination, Genetic
- Sequence Homology, Amino Acid
- Structure-Activity Relationship
- Transferases (Other Substituted Phosphate Groups)