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Article

Gene expression profiling of peripheral blood leukocytes identifies and validates ABCB1 as a novel biomarker for Alzheimer's disease.

Neurobiology of disease - 1 Sept 2011

Chen Kuang-Den, Chang Po-Tsung, Ping Yueh-Hsin, Lee Hsin-Chen, Yeh Chin-Wei, Wang Pei-Ning

Abstract excerpt

Increasing evidence has shown that the immunological reaction of leukocytes plays a crucial role in the development of neurodegenerative disorders. We conducted transcriptome analysis of leukocytes from patients of mild cognitive impairment (MCI), Alzheimer's disease (AD), as well as normal controls (NC) by oligonucleotide microarray. The differentially expressed genes of interest were selected by pathway-based...

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Source

Identifiers

PMID: 21669286
DOI: 10.1016/j.nbd.2011.05.023

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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