Article
Gene expression analysis reveals the dysregulation of immune and metabolic pathways in Alzheimer's disease.
Oncotarget - 8 Nov 2016
Chen Juan, Xie Chuncheng, Zhao Yanhong, Li Zhiyan, Xu Panpan, Yao Lifen
Abstract excerpt
In recent years, several pathway analyses of genome-wide association studies reported the involvement of metabolic and immune pathways in Alzheimer's disease (AD). Until now, the exact mechanisms of these pathways in AD are still unclear. Here, we conducted a pathway analysis of a whole genome AD case-control expression dataset (n=41, 25 AD cases and 16 controls) from the human temporal cortex tissue. Using the...
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