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Article

Targeting the Fibroblast Growth Factor Receptor (FGFR) Family in Lung Cancer.

Cells - 10 May 2021

Pacini Laura, Jenks Andrew D, Lima Nadia Carvalho, Huang Paul H

Abstract excerpt

Lung cancer is the most common cause of cancer-related deaths globally. Genetic alterations, such as amplifications, mutations and translocations in the fibroblast growth factor receptor (FGFR) family have been found in non-small cell lung cancer (NSCLC) where they have a role in cancer initiation and progression. FGFR aberrations have also been identified as key compensatory bypass mechanisms of resistance to...

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Identifiers

PMID: 34068816
DOI: 10.3390/cells10051154
PMCID: PMC8151052

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