Article
Somatic mutations of signaling genes in non-small-cell lung cancer.
Cancer genetics and cytogenetics - 1 Nov 2010
Sanders Heather R, Albitar Maher
Abstract excerpt
Lung cancer is the leading cause of cancer-related deaths, with non-small-cell lung cancer (NSCLC) accounting for approximately 85% of cases. A significant proportion of NSCLC cases are not diagnosed until a late stage, when aggressive treatments are required but often prolong survival only modestly. Recent advances in molecular characterization of NSCLC have enabled identification of numerous cell growth and...
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