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Matrix metalloproteinases in tuberculosis

9 Jun 2011

Abstract excerpt

Tuberculosis (TB) remains a global health pandemic. Infection is spread by the aerosol route and Mycobacterium tuberculosis must drive lung destruction to be transmitted to new hosts. Such inflammatory tissue damage is responsible for morbidity and mortality in patients. The underlying mechanisms of matrix destruction in TB remain poorly understood but consideration of the lung extracellular matrix predicts that...

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PMID: 21659415
DOI: 10.1183/09031936.00015411

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