Article
KIT-negative gastrointestinal stromal tumor of the abdominal soft tissue: a clinicopathologic and genetic study of 10 cases.
The American journal of surgical pathology - 1 Sept 2011
Yamamoto Hidetaka, Kojima Aya, Nagata Shigenori, Tomita Yasuhiko, Takahashi Satsuki, Oda Yoshinao
Abstract excerpt
Gastrointestinal stromal tumor (GIST) typically occurs in the gastrointestinal (GI) tract, and expresses KIT protein that is associated with KIT or platelet-derived growth factor receptor-α (PDGFRA) gene mutation. Extragastrointestinal stromal tumors (EGISTs) are a minor subset of GIST that occurs in the soft tissue outside the GI tract, and in very rare cases, these tumors can be KIT negative. We examined the...
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