Article
Cowpox virus induces interleukin-10 both in vitro and in vivo.
Virology - 15 Aug 2011
Spesock April H, Barefoot Brice E, Ray Caroline A, Kenan Daniel J, Gunn Michael D, Ramsburg Elizabeth A, Pickup David J
Abstract excerpt
Cowpox virus infection induces interleukin-10 (IL-10) production from mouse bone marrow-derived dendritic cells (BMDCs) or cells of the mouse macrophage line (RAW264.7) at about 1800 pg/ml, whereas infections with vaccinia virus (strains WR or MVA) induced much less IL-10. Similarly, in vivo, IL-10 levels in bronchoalveolar lavage fluids of mice infected with cowpox virus were significantly higher than those...
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