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Article

Identification of novel schizophrenia loci by homozygosity mapping using DNA microarray analysis.

PloS one - 1 Jan 2011

Kurotaki Naohiro, Tasaki Shinya, Mishima Hiroyuki, Ono Shinji, Imamura Akira, Kikuchi Taeko, Nishida Nao, Tokunaga Katsushi, Yoshiura Koh-ichiro, Ozawa Hiroki

Abstract excerpt

The recent development of high-resolution DNA microarrays, in which hundreds of thousands of single nucleotide polymorphisms (SNPs) are genotyped, enables the rapid identification of susceptibility genes for complex diseases. Clusters of these SNPs may show runs of homozygosity (ROHs) that can be analyzed for association with disease. An analysis of patients whose parents were first cousins enables the search for...

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Identifiers

PMID: 21655227
DOI: 10.1371/journal.pone.0020589
PMCID: PMC3105082

Genes

ACSL6
HINT1

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