Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long-term balancing selection at the blood group-related gene B4galnt2 in the genus Mus (Rodentia; Muridae).

Molecular biology and evolution - 1 Nov 2011

Linnenbrink Miriam, Johnsen Jill M, Montero Inka, Brzezinski Christine R, Harr Bettina, Baines John F

Abstract excerpt

Recent surveys of the human genome have highlighted the significance of balancing selection in relation to understanding the evolutionary origins of disease-associated variation. Cis-regulatory variation at the blood group-related glycosyltransferase B4galnt2 is associated with a phenotype in mice that closely resembles a common human bleeding disorder, von Willebrand disease. In this study, we have performed a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Flanking Region
Share to Cluster Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Evolution, Molecular

Share to Gastrointestinal Tract

Share to Linkage Disequilibrium

Share to N-Acetylgalactosaminyltransferases

Share to Selection, Genetic

Share to Species Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 21652612
DOI: 10.1093/molbev/msr150
PMCID: PMC4357812

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long-term balancing selection at the blood group-related gene B4galnt2 in the genus Mus (Rodentia; Muridae).PMID 21652612Read ↗

Selection on cis-regulatory variation at B4galnt2 and its influence on von Willebrand factor in house mice.Semantic proximity Read ↗

Evaluating the maintenance of disease-associated variation at the blood group-related gene B4galnt2 in house mice.Semantic proximity Read ↗

Long-term molecular evolutionary rate determines intraspecific genetic diversitySemantic proximity Read ↗

Multiple instances of ancient balancing selection shared between humans and chimpanzees.Semantic proximity Read ↗

Molecular Evolutionary Rate Predicts Intraspecific Genetic Polymorphism and Species-Specific Selection.Semantic proximity Read ↗

The impact of natural selection on the evolution and function of placentally expressed galectinsSemantic proximity Read ↗

The endothelial-specific regulatory mutation, Mvwf1, is a common mouse founder allele.Semantic proximity Read ↗

Detection of shared balancing selection in the absence of trans-species polymorphismSemantic proximity Read ↗

Functional organization of the genome may shape the species boundary in the house mouse.Semantic proximity Read ↗

Trans-species polymorphism in humans and the great apes is generally maintained by balancing selection that modulates the host immune responseSemantic proximity Read ↗

Recent Selection Changes in Human Genes under Long-Term Balancing Selection.Semantic proximity Read ↗

Interspecific introgressive origin of genomic diversity in the house mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.