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Article

GSK-3β, FYN, and DYRK1A: Master Regulators in Neurodegenerative Pathways

23 Aug 2021

Abstract excerpt

Protein kinases (PKs) have been recognized as central nervous system (CNS)-disease-relevant targets due to their master regulatory role in different signal transduction cascades in the neuroscience space. Among them, GSK-3β, FYN, and DYRK1A play a crucial role in the neurodegeneration context, and the deregulation of all three PKs has been linked to different CNS disorders with unmet medical needs, including...

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PMID: 34445804
DOI: 10.3390/ijms22169098

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