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Article

Alterations of ATM and CADM1 in chromosomal 11q22.3-23.2 region are associated with the development of invasive cervical carcinoma.

Human genetics - 1 Dec 2011

Mazumder Indra Dipanjana, Mitra Sraboni, Roy Anup, Mondal Ranajit Kumar, Basu Partha Sarathi, Roychoudhury Susanta, Chakravarty Runu, Panda Chinmay Kumar

Abstract excerpt

To understand the importance of chr11q22.3-23.2 region in the development of cervical cancer, we have studied the genetic and epigenetic alterations of the candidate genes ATM, PPP2R1B, SDHD and CADM1 in cervical intraepithelial neoplasia (CIN) and cervical carcinoma (CACX) samples. Our study revealed low expression and high alterations (methylation/deletion) (55-59%) of ATM and CADM1 genes along with poor...

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Identifiers

PMID: 21643982
DOI: 10.1007/s00439-011-1015-8

Genes

ATM
CADM1
CHEK1
SDHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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