Article

Down-regulation of FA-BRCA pathway in the molecular pathogenesis of uterine cervical carcinoma of Indian population: clinical and prognostic implications

2022-08-15

Abstract excerpt

<h4>Objective: </h4> Our study was aimed to understand the importance of FA-BRCA pathway genes in cervical carcinogenesis and their association with the prognosis of the disease. <h4>Material: </h4> and methods: we analysed the molecular profiles of the key regulatory genes of FA-BRCA pathway (BRCA1, BRCA2, FANCC, FANCD2) in 109 cervical lesions at different clinical stages and validated in different bioinformatic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e27b1d1e-4772-52ac-acbd-9403a615b006
DOI: 10.21203/rs.3.rs-1944207/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Down-regulation of FA-BRCA pathway in the molecular pathogenesis of uterine cervical carcinoma of Indian population: clinical and prognostic implicationsDOI 10.21203/rs.3.rs-1944207/v1Read

Genomic Profiling of Chinese Cervical Cancer Patients Reveals Prevalence of DNA Damage Repair Gene Alterations and Related Hypoxia FeatureSemantic proximity Read

Exploring the p53 connection of cervical cancer pathogenesis involving north-east Indian patients.Semantic proximity Read

A novel DNA damage repair-related gene signature predicting survival, immune infiltration and drug sensitivity in cervical cancer based on single cell sequencingSemantic proximity Read

Transcriptomes of cervical cancer provide novel insights into dysregulated pathways, potential therapeutic targets, and repurposed drugsSemantic proximity Read

Systematic Analysis of the Therapy Resistance Genes and their Prognostic Relevance in Cervical CancerSemantic proximity Read

Identification of Key Genes and Pathways associated with Chemotherapy and Radiotherapy Sensitivity in Locally Advanced Cervical CancerSemantic proximity Read

Identification of Key Genes and Pathways Associated with Chemotherapy and Radiotherapy Sensitivity in Locally Advanced Cervical CancerSemantic proximity Read

Expression profiling of cervical cancers in <scp>I</scp>ndian women at different stages to identify gene signatures during progression of the diseaseSemantic proximity Read

miRNAs role in cervical cancer pathogenesis and targeted therapy: Signaling pathways interplaySemantic proximity Read

Moving Forward in Cervical Cancer: Enhancing Susceptibility to DNA Repair Inhibition and Damage, an NCI Clinical Trials Planning Meeting ReportSemantic proximity Read

Epigenetics and cervical cancer: from pathogenesis to therapySemantic proximity Read

A Review: Genetic Mutations as a Key to Unlocking Drug Resistance in Cervical Cancer.Semantic proximity Read