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Article

Exaggerated Eye Growth in IRBP-Deficient Mice in Early Development

4 Jun 2011

Abstract excerpt

PURPOSE: Because interphotoreceptor retinoid-binding protein (IRBP) is expressed before being needed in its presumptive role in the visual cycle, we tested whether it controls eye growth during development. METHODS: The eyes of congenic IRBP knockout (KO) and C57BL/6J wild-type (WT) mice ranging in age from postnatal day (P)2 to P440 were compared by histology, laser micrometry, cycloplegic photorefractions, and...

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PMID: 21642628
DOI: 10.1167/iovs.10-7129

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