Article
Macrophage infiltration and smooth muscle cells content associated with haptoglobin genotype in human atherosclerotic carotid plaques.
Angiology - 1 Apr 2012
Lioupis Christos, Barbatis Calypso, Lazari Paraskevi, Liasis Nikolaos, Klonaris Christos, Georgopoulos Sotirios, Andrikopoulos Vasilios, Bastounis Elias
Abstract excerpt
We assessed the association between the haptoglobin (Hp) genotype and 2 common indicators of atherosclerotic plaque instability: macrophage infiltration and the smooth muscle cell (SMC) content. A total of 70 consecutive patients who underwent carotid endarterectomy were included in the study. For immunohistochemical study the anti-CD68 and anti-a-actin antibodies were used on adjacent serial sections; 36 plaques...
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