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Article

An OGG1 polymorphism is associated with mitochondrial DNA content in pesticide-exposed fruit growers.

Toxicology - 5 Sept 2011

Huang Pei-Lin, Wang Ming-Fuu, Lee Hong-Shen, Liu Yi-Jie, Chen Chun-Chieh, Chen Shiuan-Chih, Lai Jim-Shoung, Wong Ruey-Hong

Abstract excerpt

Exposure to pesticides has the capacity to cause mitochondrial dysfunction. An increase mitochondrial DNA (mtDNA) content has also been suggested to relate with DNA damaging agent. In mitochondria, the manganese superoxide dismutase (MnSOD) is a scavenger of reactive oxygen species, and the 8-oxoguanine DNA glycosylase (OGG1) is the major DNA glycosylase for the repair of 8-oxoG lesions. However, the alteration...

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Source

Identifiers

PMID: 21640155
DOI: 10.1016/j.tox.2011.05.001

Genes

OGG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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