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Article

Polymorphisms in metabolic GSTP1 and DNA-repair XRCC1 genes with an increased risk of DNA damage in pesticide-exposed fruit growers.

Mutation research - 31 Jul 2008

Wong Ruey-Hong, Chang Shu-Yuan, Ho Shu-Wei, Huang Pei-Lin, Liu Yi-Jie, Chen Yu-Ching, Yeh Yu-Hsuan, Lee Hong-Shen

Abstract excerpt

Pesticide exposure is associated with various neoplastic diseases and congenital malformations. Previous studies have indicated that pesticides may be metabolized by cytochrome P450 3A5 or glutathione S-transferases. DNA-repair genes, including X-ray repair cross-complementing group 1 (XRCC1) and xeroderma pigmentosum group D (XPD), may also be implicated in the process of pesticide-related carcinogenesis. Thus,...

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Source

Identifiers

PMID: 18603015
DOI: 10.1016/j.mrgentox.2008.06.005

Genes

XRCC1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms in metabolic GSTP1 and DNA-repair XRCC1 genes with an increased risk of DNA damage in pesticide-exposed fruit growers.PMID 18603015Read ↗

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