Article
Effects of DTNBP1 genotype on brain development in children.
Journal of child psychology and psychiatry, and allied disciplines - 1 Dec 2011
Tognin Stefania, Viding Essi, McCrory Eamon J, Taylor Lauren, O'Donovan Michael C, McGuire Philip, Mechelli Andrea
Abstract excerpt
BACKGROUND: Schizophrenia is a neurodevelopmental disorder, and risk genes are thought to act through disruption of brain development. Several genetic studies have identified dystrobrevin-binding protein 1 (DTNBP1, also known as dysbindin) as a potential susceptibility gene for schizophrenia, but its impact on brain development is poorly understood. The present investigation examined for the first time the...
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