Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The potential role of interferon-regulatory factor 7 among Taiwanese patients with systemic lupus erythematosus.

The Journal of rheumatology - 1 Sept 2011

Lin Li-Hsin, Ling Pin, Liu Ming-Fei

Abstract excerpt

OBJECTIVE: Type I interferons (IFN), especially IFN-α, have been proposed to underlie the pathogenesis of systemic lupus erythematosus (SLE). Members of the IFN regulatory factor (IRF) family, which regulate IFN expression, have been implicated as risk factors for SLE. Our aims were to investigate the expression of IRF7 and its correlation with disease activity and to explore the association in Taiwanese patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Frequency
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interferon-alpha

Share to Leukocytes, Mononuclear

Share to Lupus Erythematosus, Systemic

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to Taiwan

Source

Identifiers

PMID: 21632682
DOI: 10.3899/jrheum.101004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The potential role of interferon-regulatory factor 7 among Taiwanese patients with systemic lupus erythematosus.PMID 21632682Read ↗

Association of the IRF5 rs2070197 polymorphism with systemic lupus erythematosus: a meta-analysis.Semantic proximity Read ↗

IRF7, a functional factor associates with systemic lupus erythematosus.Semantic proximity Read ↗

Association of the polymorphisms rs179008 (TLR7), rs2004640 (IRF5), rs1800795 (IL-6) and rs2280788 (CCL5) with systemic lupus erythematosus in women of Mayan ethnicity from Yucatan.Semantic proximity Read ↗

Emerging role of SIGIRR rs7396562(T/G) polymorphism in systemic lupus erythematosus in a Chinese population.Semantic proximity Read ↗

Genetic polymorphisms in genes involved in the type I interferon system (STAT4 and IRF5): association with Asian SLE patients.Semantic proximity Read ↗

Single-nucleotide polymorphisms of IRF8 gene are associated with systemic lupus erythematosus in Chinese Han population.Semantic proximity Read ↗

Variants in the interferon regulatory factor 5 gene confer genetic risk for systemic lupus erythematosus in a Han Chinese population.Semantic proximity Read ↗

Interferon regulatory factors: critical mediators of human lupus.Semantic proximity Read ↗

Interferon Regulatory Factor 5 in the Pathogenesis of Systemic Lupus ErythematosusSemantic proximity Read ↗

No evidence for a genetic association of IRF4 with systemic lupus erythematosus in a Chinese population.Semantic proximity Read ↗

Clinical features and expression of type I interferon-inducible genes in systemic lupus erythematosus patients harboring rs1143679 polymorphism in China: a single-center, retrospective study.Semantic proximity Read ↗

Interferon-gamma (IFN-γ) intronic variant (rs2430561) is a risk factor for systemic lupus erythematosus: Observation from a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.