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Article

Chronic pancreatitis: an update on genetic risk factors.

Current opinion in gastroenterology - 1 Sept 2018

Weiss Frank U, Skube Mariya E, Lerch Markus M

Abstract excerpt

PURPOSE OF REVIEW: Genetic mutations in genes within and outside of the trypsin-dependent pathologic pathway have been found to be associated with chronic pancreatitis. This review highlights recent developments. RECENT FINDINGS: CTRB1-CTRB2 has been identified as a new risk locus for chronic pancreatitis and the disease mechanism may involve trypsin degradation. Misfolding mutations in PRSS1, CPA1, and CEL, as...

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Source

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Identifiers

PMID: 29901518
DOI: 10.1097/MOG.0000000000000461
PMCID: PMC9622341

Genes

CEL
CPA1
CTRB1
CTRB2
PRSS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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