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New insights on the pathomechanisms of inflammatory bowel disease.

Journal of digestive diseases - 1 Sept 2013

Abdullah Murdani, Syam Ari Fahrial, Simadibrata Marcellus, Gunawan Jeffri, Makmun Dadang, Rani Abdul Aziz

Abstract excerpt

Pathogenesis of inflammatory bowel disease (IBD) remains an enigma on whether germs, genes or a combination of these two with excessive immune responses to gut-associated bacteria explicates its pathomechanisms. The incidence of IBD is 0.76747 per 100,000 in Central Indonesia, as shown in the Project Indonesian IBD ACCESS 2012 progress report. This result, together with other epidemiological studies in Asia, may...

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Endoplasmic Reticulum Stress
Gene-Environment Interaction
Genetic Predisposition to Disease
Immunity, Cellular
Inflammatory Bowel Diseases

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PMID: 23764259
DOI: 10.1111/1751-2980.12081

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