Article
Recent understanding of IBD pathogenesis: implications for future therapies.
Inflammatory bowel diseases - 1 Nov 2006
Kucharzik Torsten, Maaser Christian, Lügering Andreas, Kagnoff Martin, Mayer Lloyd, Targan Stephan, Domschke Wolfram
Abstract excerpt
The inflammatory bowel diseases (IBD) are comprised of two major phenotypes, Crohn's disease (CD) and ulcerative colitis (UC). Research over the last couple of years has led to great advances in understanding the inflammatory bowel diseases and their underlying pathophysiologic mechanisms. From the current understanding, it is likely that chronic inflammation in IBD is due to aggressive cellular immune responses...
Topics
- Bacterial Infections
- Colitis, Ulcerative
- Colon
- Crohn Disease
- Genetic Predisposition to Disease
- Humans
- Inflammation Mediators
- Inflammatory Bowel Diseases
- Intestinal Mucosa
- Risk Factors