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Article

G-308A TNF-alpha polymorphism is associated with an increased risk of hepatocellular carcinoma in the Turkish population: case-control study.

Cancer epidemiology - 1 Oct 2009

Akkiz Hikmet, Bayram Süleyman, Bekar Aynur, Ozdil Burhan, Akgöllü Ersin, Sümbül Ahmet Taner, Demiryürek Haluk, Doran Figen

Abstract excerpt

BACKGROUND: Tumor necrosis factor-alpha (TNF-alpha) is a pro-inflammatory cytokine that may act as an endogenous tumor promoter. A genetic polymorphism of TNF-alpha gene at position -308 promoter region is involved in the regulation of expression level and has been found to be associated with susceptibility to various types of cancer. METHODS: To determine the association of the TNF-alpha gene G-308A polymorphism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19683483
DOI: 10.1016/j.canep.2009.06.001

Genes

TNF

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