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Article

hTERT regulation by NF-κB and c-myc in irradiated HER2-positive breast cancer cells.

International journal of radiation biology - 1 Jun 2011

Papanikolaou Vassilis, Athanassiou Evangelos, Dubos Stephanie, Dimou Ioannis, Papathanasiou Ioanna, Kitsiou-Tzeli Sofia, Kappas Constantin, Tsezou Aspasia

Abstract excerpt

PURPOSE: Telomerase activity (TA), frequently observed in cancer, compensates for telomere shortening thus preventing cell senescence and conferring resistance to therapy. In the present study, we investigated the expression of human telomerase reverse transcriptase (hTERT) and TA and their regulation, as well as apoptotic rates and correlation with the presence of human epidermal growth factor receptor 2 (HER2),...

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Identifiers

PMID: 21627565
DOI: 10.3109/09553002.2011.572112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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