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Article

NF-kappaB-mediated HER2 overexpression in radiation-adaptive resistance.

Radiation research - 1 Jan 2009

Cao Ning, Li Shiyong, Wang Zhaoqing, Ahmed Kazi Mokim, Degnan Michael E, Fan Ming, Dynlacht Joseph R, Li Jian Jian

Abstract excerpt

The molecular mechanisms governing acquired tumor resistance during radiotherapy remain to be elucidated. In breast cancer patients, overexpression of HER2 (human epidermal growth factor receptor 2) is correlated with aggressive tumor growth and increased recurrence. In the present study, we demonstrate that HER2 expression can be induced by radiation in breast cancer cells with a low basal level of HER2....

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Source

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Identifiers

PMID: 19138055
DOI: 10.1667/RR1472.1
PMCID: PMC2659759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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